• Dr. Alla Arutcheva

Leaky Gut. Have gut problems? Suspect leaky gut? Do not give up! We have solutions for you!

Updated: Nov 27, 2019




Leaky gut (intestinal permeability) contributes to numerous inflammatory gastrointestinal, non-intestinal diseases (skin, liver, brain) and autoimmune diseases.

Our intestinal tract is lined by layers of epithelial cells, which are connected by cell-cell junctions. This junction maintains tissue integrity, creates a barrier to control the passage of water, molecules, cells, and pathogens across epithelial layers, and protects against disease.

Even micro holes in the intestinal epithelial barriers can lead to serious pathological consequences, infection and inflammation.



What are risk factors for leaky gut

Infection


Bacterial overgrowth (SIBO), yeast overgrowth, virus, parasites. Intestinal infection caused by E.coli, Salmonella, Klebsiella, Staphylococcus aureus and other pathogenic agents. Helicobacter pylori is known to directly increase epithelial permeability

Metabolic


High blood glucose, diabetes, obesity contribute to disruption on the intestinal epithelial layer

Medications


Antibiotics, corticosteroids, non-steroidal anti-inflammatory drugs (aspirin, ibuprofen), antacid, and many other medications

Diet and Food Sensitivity


The food that is processed, loaded with additives and preservatives, genetically modified, overloaded with sugar, and containing gluten and fructan (for gluten-sensitive individuals). Food deficient in nutrients.

Alcohol


Excessive and chronic alcohol consumption

Hormones


Low level of estradiol, testosterone, hypothyroid

Enzymes


Deficiency of carbohydrase including lactase, fructase, sucrase, galactosidase

Stress

Increased level of cortisol, low serotonin, chronic fatigue, depression


In some patients causes may be at work simultaneously


Leaky gut symptoms:

· bloating, gas

· food sensitivities

· cravings for sugar,